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Table 1 Major features of IS4 subgroups and newly defined families

From: IS4 family goes genomic

Families

Sub-groups

Typical size range (bp)

Endsa

YREKb

Direct repeat length (bp)

IS4

IS231

1450 – 5400

CAT-------AA--TAA---

Y

10 – 12

 

ISH8

1400 – 1800

CAT-----------T-----

Y

10

 

IS4Sa

1150 – 1750

CA------T-----------

Y

8 – 10

 

IS4

1400 – 1650

-AATR--------WTW----

Y

10 – 13

 

IS10

1200 – 1350

CT------------------

Y

9

 

IS50

1350 – 1550

CW------Y---CA-A--W-

Y

8 – 9

 

ISPepr1

1500 – 1600

YT-AA-YTT---A-------

Y

7 – 8

IS701

-

1400 – 1550

---YACT-Y--YR-------

N

4

ISH3

-

1225 – 1500

CRGT----------------

N

4 – 5

IS1634

-

1500 – 2000

C-----YT------------

N

5 – 6

  1. aConserved terminal based pairs. Capital letters refer to mostly conserved bases. W, A or T; R, G or A; Y, T or C.
  2. bPresence (Y) or absence (N) of YREK motif.
  3. The new organization of family IS4 is shown together with emerging families. The table summarizes DNA characteristics with transposase motifs and target site duplication lengths. The two major differences between IS4 and emerging families are presence or absence of the YREK motif and dissimilar lengths of DRs.