Figure 3

Target sites : duplications and conservations. Consensus sequences of in silico reconstructed and aligned target sites (5' to 3') typical for each subgroup or family. Only ISs found at least at five different genomic locations and flanked by DRs were considered, as well as elements described previously in literature. Each box represents one base position. Target sites are divided in three parts. The central sequence, which is duplicated upon insertion, is flanked by one upstream (left) and one downstream (right) target arm. Ten bps of each arm are shown. The number of target sites considered for each element is indicated. If more than one element displayed similar insertion specificity, their insertion sites were combined into a single line and their names listed above it. Gray boxes inside a duplication consensus indicate that DRs of variable length can be found for the given element. W, A or T; S, G or C; R, A or G; Y, T or C. * 'IS231' stands for following elements: IS231A, C, F, M, S, T, U, Y, ISBce4, 5, 6, 11, 12 and ISBth5. ** For the 6000 sites, see references [75–77].