Table 3 Conserved motifs in PIG-A proteins from eukaryotes.

CM1

[STC]-D-F-F-[YFC]-P-X-X-G-G-[VI]-E-X-H-X-[YF]

CM2

G-[HFNL]-[KRS]-[VI]-[VI]-[ITV]-X-T-[HRN]-[AQNFSGK]-[YN]-X-X-[RTC]-X-G-[VI]

CM3

[GY]-[LIM]-[KT]-V-Y-[YH]-X-P

CM4

[PLA]-X-X-[RS]-X-[ILV]-[FLVH]-[VIRLY]-[RE]-[EH]-X-[IVF]-X-[IV]-[ILV]-H-[SGAC]-H-[GQSA]-[STAN]-[FLATY]-S

CM5

G-X-[KPQRS]-[TAV]-[VFCI]-[FLY]-T-[DE]-H-S-[LM]

CM6

I-[CAS]-V-S-X-[TCEIV]-[STCGN]-[KRE]-[ED]-N-[TML]-[VCIRS]-[LVIM]-[RL]

CM7

[PFK]-X-X-X-X-[VIMT]-[VI]-[PG]-N-[AI]

CM8

[IV]-[VAI]-[VIF]-[VILMA]-X-R-[LM]-[VYFT]-[YPQF]-[RN]-K-G-X-D-L

CM9

[FWVY]-[ILVY]-[VI]-[GAV]-G-[EDNS]-G-P-[KMR]

CM10

[GC]-[HDQ]-I-[FYG]-[LIV]-[NHI]-X-S-[LY]-[TL]-E-[AG]-[FY]-[CGS]-X-[AVIS]-[IL]-[VIL]-E-[AS]-[AL]-[SQ]-[CE]-[GNA]-[LC]

CM11

[STA]-[TS]-X-V-G-G-[IVT]-[PDSK]-[ES]-V-[LY]-[PK]

CM12

Y-[STDN]-[WP]-X-X-[VI]-[AS]-X-[RK]-[TV]-[EVYQ]-X-[VIS]-[YH]