Directional and balancing selection in human beta-defensins

Table 2 Human-macaque divergence and human coding polymorphisms of genes positively selected in catarrhine primates.

Gene	Human – macaque non-synonymous fixed changes	Human – macaque synonymous fixed changes	Human non-synonymous polymorphisms	Human synonymous polymorphisms	Rs number	Human non-synonymous polymorphic sites	Indigenous Australians	UK population	Other sub-saharan Africans	Mbuti/Biaka	Agriculturalists	Hunter-Gatherers	Fisher's exact test p value (not corrected for multiple tests)	African	Non-African	Fisher's exact test p value (not corrected for multiple tests)
DEFB127	8	6	4	1	16995685	R71S	4	8	0	1	8	5	0.175	1	12	0.002
					-	R71H	0	0	0	2	0	2	0.288	2	0	0.208
					12624954	G31R	4	8	0	1	8	5	0.175	1	12	0.002
					-	K58R	0	0	1	0	1	0	0.459	1	0	0.459
DEFB120	13	2	3	0	-	H28R	0	0	1	3	1	3	0.371	4	0	0.040
					-	R46C	1	0	0	0	0	1	0.541	0	1	0.541
					-	89EL	0	0	1	3	1	3	0.371	4	0	0.040
DEFB132	12	8	5	2	-	W41S	0	0	1	2	1	2	0.561	3	0	0.092
					-	P63Q	0	0	3	1	3	1	0.248	4	0	0.040
					-	L70F	0	0	1	2	1	2	0.561	0	3	0.152
					-	V93I/T	4	0	0	2	0	6	0.021	2	4	0.418
					-	V93A/T	3	0	1	9	1	12	0.002	10	3	0.015
DEFB118	11	7	2	0	-	C34R	0	1	0	0	1	0	0.459	0	1	0.541
					-	I56V	0	0	1	4	1	4	0.234	5	0	0.017
DEFB1	6	7	2	1	-	F24C	0	0	0	1	0	1	0.541	1	0	0.459
					2738047	V38I	0	0	0	1	0	1	0.541	1	0	0.459
n	50	30	16	4	-	16	20	20	14	20	34	40	-	34	40	-

ISSN: 2730-7182