Figure 5

Evolution of protostome GATA factors. Alternate scenarios for the early/orthologous (S1) or late/convergent (S2) evolution of the arthropod and lophotrochozoan GATA456 gene clusters. Names at a node represent the name of the clade of organisms, and the time since the last common ancestor is given for some nodes in million years (mya) (tree topology, dates, and nomenclature from [19–21]). Boxes represent individual GATA genes, with GATA123 orthologs in blue, and GATA456 orthologs in red. Light shaded nematode GATAs represent predictions based mainly upon functional conservation. Linked genes are represented with a connected line, and identified via their terminal letters (see Materials and Methods).