Figure 5

Annotated tree of a regulatory region of Nanog. The NCBI common species tree [28,29] for Dasypus novemcinctus, Felis catus, Canis lupus familiaris, Bos taurus, Erinaceus europaeus, Sorex araneus, Equus caballus, Pan troglodytes, Homo sapiens, Macaca mulatta, Mus musculus, Rattus norvegicus, Loxodonta africana, Echinops telfairi, and Monodelphis domestica, labeled with the predictions from Figure 2. The boxes contain TFBS predictions for each node in the tree. We use the TFBS names of Mapper and Genomatix. According to Dollo parsimony the TFBSs written in green are gained at the corresponding node, the red ones are lost. In blue we list TFBSs that are estimated to be present, for some of the (ancestral) species. This figure shows a clipping of the Nanog tree only, for the full image please see Additional file 2.