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Figure 7 | BMC Evolutionary Biology

Figure 7

From: Reducing the false positive rate in the non-parametric analysis of molecular coevolution

Figure 7

Representation of the different types of coevolution strengths. In this example we represent a phylogeny of 20 related sequences the amino acid states at each sequence is represented by one of the four different symbols, circles, star, sqaure and triangle. Coevolution in the simulation data set was set at three different strengths: 10% with 10 of the sequences (2 sequences) sharing the same amino acid state (circle for example), a different 10% of sequences was sharing another pattern or amino acid state (triangles), 40% another state (star) and the remaining 40% sharing the final state (square). The same rationale applied to the case of 20% as well as 25% coevolution strengths. These levels of coevolution arer considered low (yielding low Mutual Information values, the case of 10%), medium (greater MI values, 20%) and strong coevolution (the greatest possible MI values, 25%).

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