Skip to main content

Table 1 Parameter estimates for the GPR50, mel1 a, b, c under Model A and the effects of codon usage bias on LRTs (n = 29)

From: GPR50 is the mammalian ortholog of Mel1c: Evidence of rapid evolution in mammals

Model p l Parameters estimates Positively selected sites
M0: one-ratio 103 -15666. 37 ω = 0.0655  
M1a (neutral) 104 -15620.766436 p0 = 0.967, p1 = 0.032  
Branch-site model:     
GPR50:
Model A
106 -15608.39 p0 = 0.714, p1 = 0.026
(p2 + p3) = 0.258
ω2 = 1
 
mel1a:
Model A
106 -15613.74 p0 = 0.883, p1 = 0.031
(p2 + p3) = 0.085
ω2 = 999
Site for foreground lineage:
183V
mel1b:
Model A
106 -15611.52 p0 = 0.833, p1 = 0.031
(p2 + p3) = 0.135
ω2 = 999
98K102Q 147I 227D
mel1c:
Model A
106 -15617.63 p0 = 0.955, p1 = 0.032
(p2 + p3) = 0.011
ω2 = 555.04
278A
  1. Note: p is the number of free parameters for the ω ratios. Parameters indicating positive selection are written in bold. Tests comparing sites-specific model M1a and branch-site model A are significant at 1%, df = 2. Sites potentially under positive selection were identified using GPR50 from O. aries according to the Bayes empirical Bayes analyses for Model A (at P > 0.95). These sites are shown in Fig. 3.