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Table 5 Sequence Identities of the Ciona VDR/PXR to Other Nuclear Hormone Receptors

From: Evolution of pharmacologic specificity in the pregnane X receptor

Receptor

% Identity to Ciona VDR/PXR in DBD

% Identity to Ciona VDR/PXR in LBD

Human PXR

61.8

22.5

Mouse PXR

60.3

21.5

Chicken PXR

63.2

23.7

Xenopus laevis PXRα

64.7

20.3

Fugu PXR

67.6

19.8

Human VDR

67.6

17.1

Zebrafish VDR

70.6

21.8

Sea lamprey VDR

73.5

20.8

Human CAR

60.3

26.8

Mouse CAR

55.9

23.2

Human FXR

54.4

23.1

Zebrafish FXR

55.9

24.0

Ciona FXR

55.2

21.9

Human LXRa

54.4

21.9

Zebrafish LXR

54.4

19.8

Ciona LXR

52.9

19.3