From: The phylogeny of the mammalian heme peroxidases and the evolution of their diverse functions
Superfamily (EC no.) | Chromosomal Location (Human) | Tissue Expression | Biological Function |
---|---|---|---|
MPO (1.11.1.7) | 17 | Neutrophils, mono-nuclear phagocytes | Microbicidal activity |
EPO (1.11.1.7) | 17 | Eosinophils | Microbicidal activity |
LPO (1.11.1.7) | 17 | Milk, saliva, tears and other secretions | Bacteriostatic and bactericidal activity |
TPO (1.11.1.8) | 2 | Thyroid cell surface and cytoplasm | Thyroid hormone biosynthesis |