Figure 2

Analysis of rice protein XP_478746 and BLAST hits. The PFAM domain architectures of XP_478746, annotated as a "TIR/P-loop/LRR disease resistance protein-like protien" (sic) from Oryza sativa, and its closest BLAST homologs are shown. XP_478746 contains a TIR domain only with no room for the P-loop and LRR regions; the sequence is therefore misannotated. We expect XP_478746 was annotated based on local similarity to a sequence such as AAM28917 (annotated as a "putative TIR/NBS/LRR disease resistance protein" from Pinus taeda), which does contain the NB-ARC and LRR domains. See text for details.