Figure 1

Mixed patterns of variation within array Tb109c (hypothetical protein, Tb10.389.0740). A. GENECONV output after analysis of an alignment of gene copies 1–3. Similarity was inferred from the non-random distribution of shared polymorphisms among any two sequences; the likelihood of each phylogenetic grouping is represented by coloured rectangles: copies 1 and 2 as closest relatives (green); 1 and 3 (red); 2 and 3 (blue). B. Diagram of the chromosomal position of Tb109c. DNA strands are shown in grey, scale is in base-pairs. The tandem array is coloured red, other annotated genes are green and hypothetical genes are coloured blue. The identity of UTRs around each gene duplicate is denoted by geometric symbols; identical UTRs possess the same symbol. C. Phylogenetic tree for Tb109c homologs from four species; orthology is retained by the divergent fourth duplicate, producing a distinct clade (shaded). Values are bootstrap proportions out of 500.