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Figure 3 | BMC Evolutionary Biology

Figure 3

From: Control systems for membrane fusion in the ancestral eukaryote; evolution of tethering complexes and SM proteins

Figure 3

Sequence relationships between tethering factor subunits. Panel A, intercomplex relationships, panel B; intracomplex relationships. Sequence connections between subunits are colour-coded for clarity, and are based on PSI-BLAST hits, but the choice of colour is arbitrary. In panel A, the individual connections have been gathered together into grey ribbons between the complexes for clarity. Note that PSI-BLAST analyses retrieve multiple subunits of GARP, COG and exocyst in a reciprocal manner, while only two such associations are identified between Dsl1 and exocyst. HOPS and TRAPP are not interconnected with the other tethering complexes.

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