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Figure 2 | BMC Evolutionary Biology

Figure 2

From: Evolution of a novel subfamily of nuclear receptors with members that each contain two DNA binding domains

Figure 2

Alignment of the deduced peptide sequences of DNA binding domains of 2DBD-NRs. Each DBD is boxed with a solid line, P-box sequences (bold letters) are boxed with a dashed line. Stars identify the conserved cysteine residues that comprise the zinc finger of each DBD. Dashes indicate gaps in the sequence. The deduced amino acid sequence between DBDs for the NR from species other than S. mansoni is indicated with dots as we could not differentiate in the in silico analysis, exon sequence from intron sequence. All 2DBDs possess a P-box sequence of CEACKK in the first DBD and a P-box sequence of CEGCKG in the second DBD. Sm: flatworm Schistosoma mansoni, Se: flatworm Schmidtea mediterranea, Dj: flatworm Dugesia japonica, Lg: mollusk Lottia gigantea, Dp: arthropod Daphnia pulex.

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