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Table 6 Compensation analysis results for the MAP data set.

From: Detecting groups of coevolving positions in a molecule: a clustering approach

PDB Size Weight Stat. Nmin p-value FDR 3D dist. 3D p-value
CYS59, THR99, LYS141, SER231 4 Volume 0.68 147.26 3e-04*** yes 29.66 0.1289
TRP221, ASP227 2 Grantham 0.61 260.63 5e-04*** yes 18.13 0.1688†
LEU20, PRO34, ALA55, ASP90, SER132, VAL157, TRP221, ASP227 8 Polarity 0.75 9.96 8e-04*** yes 38.38 0.1548
GLY122, LEU230 2 Charge 0.49 3.78 9e-04*** yes 7.44 0.002**‡
HIS63, TYR134, GLU180, GLU190, PRO197, ASP242 6 Charge 0.7 3.89 0.0016** yes 35.58 0.1678
GLN154, GLU158 2 Charge 0.48 4.09 0.0017** yes 5.96 0.001***‡
PHE105, LYS111 2 Volume 0.47 267.57 0.0031** yes 20.61 0.2458
VAL24, LYS67, ILE101 3 Volume 0.58 210.55 0.0033** yes 15.15 0.002**
ASP227, HIS236 2 Charge 0.49 3.15 0.0046** yes 27.22 0.5255
THR225, GLY244 2 Grantham 0.51 258.01 0.0064** no 34.16 0.7802
VAL157, THR202 2 Grantham 0.47 310.7 0.0073** no 18.42 0.1788
ARG19, GLU23, ASN46, VAL50 4 Charge 0.62 5.02 0.0086** yes 16.04 0.001***
ALA17, ILE153, TRP221, THR222 4 Volume 0.66 126.09 0.0088** no 26.58 0.0589.†
  1. Legends are the same as in table 5.