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Table 2 Summary of the Phylogenetic Analysis of Gene Families

From: An insight into the phylogenetic history of HOX linked gene families in vertebrates

Family Name

Hsa2

Hsa7/3*

Hsa12

Hsa17

Consistency with HOX Phylogeny

Topology

ERBB

ERBB4

EGFR

ERBB3

ERBB2

-

(((17, 7)2)12)

97,98

Collagen

COL3A1

COL5A2

COL1A2

COL2A1

COL1A1

-

((((12,17)7)2)2)

93,92,83

IGFBP

IGFBP2

IGFBP5

IGFBP1

IGFBP3

IGFBP6

IGFBP4

-

((17, 7)2)

((7, 2)12)99,91

INTB

ITGB6

ITGB5*

ITGB7

ITGB3

-

(((3, 17)2)12)

98,99

MYL

MYL1

-

MYL6

MYL4

-

((17, 2)12)

87

SP

Sp3

Sp4

Sp1

Sp2

Yes

(((12,2)7)17)

98,89

ZNFN1A

ZNFN1A2

ZNFN1A1

ZNFN1A4

ZNFN1A3

-

(((7,17)2)12)

94,90

INHB

INHBB

INHBA

INHBC

INHBE

-

-

((7,2)12)

93

SLC4A

SLC4A3

SLC4A2

-

SLC4A1

-

((7,2)17)

85

GLI

GLI2

GLI3

GLI1

-

-

((7,2)12)

99

HH

IHH

SHH

DHH

 

-

((7,2)12)

97

  1. For each gene family the chromosomal location and topologies (in the Newick format) of those genes are given, which arose through duplications after the invertebrates-vertebrates split and before the tetrapods-fishes divergence. The percentage bootstrap support of the internal branches is given below each relevant topology.