Figure 2

Comparison of hydropathic profiles for selected ependymin proteins. The hydropathic profiles of two previously recognized ependymin proteins, goldfish 1 (1Carassius) and human (Epdr1_Homo) are compared with the profiles of a subset of the new members of the ependymin protein family that we are reporting. The working names used in this study are given in parenthesis. Name equivalence is as follows: Zebrafish 1 (Dan_LvItEm), Zebrafish 2 (Danio_MERP), Shark (Shark_Squa), Tunicate (Diplo_Tun), Oyster (Oyster_Cvi). [See additional file 1: Table_S1 and additional file 3: Table_S2 for additional name identifiers such as GenBank accession numbers]. All sequences are complete except for the human in which the first 20 amino acids have been trimmed to facilitate the profile comparison with the other sequences. The vertical scale represents the hydropathic score for each amino acid and the horizontal scale shows the relative position in each protein. Scores above zero are considered hydrophobic while those below are considered hydrophilic. The relative position of the hydrophobic N-terminal signal peptide for each sequence is shaded.