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Figure 1 | BMC Evolutionary Biology

Figure 1

From: Functional evolution of the vitamin D and pregnane X receptors

Figure 1

Chemical structures of 1α,25-(OH)2-vitamin D3 (calcitriol), 1α-hydroxyvitamin D2, testosterone, 5α-petromyzonol 24-sulfate (major sea lamprey bile salt), 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), and 6-formylindolo [3,2-b]carbazole. Select bond positions are numbered for the vitamins, testosterone, and 5α-petromyzonol 24-sulfate, and the lettering of the steroidal rings is indicated for calcitriol, 1α-hydroxyvitamin D2, and testosterone. The carbon atoms numbered for testosterone indicate the sites of hydroxylation in the species studied in this report.

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