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Table 1 Relationship between dog CEA family members and human and mouse orthologs

From: Species-specific evolution of immune receptor tyrosine based activation motif-containing CEACAM1-related immune receptors in the dog

 

ortholog

L

N1

A1

B1

A2

B2

N2

TM

Cyt

CEACAM1

human

64 (47)

73 (56)

79 (68)

83 (76)

75 (60)

  

63 (48)

79 (61)

 

mouse

57 (47)

62 (42)

74 (64)

80 (66)

71 (58)

  

67 (64)

78 (65)

CEACAM16

human

86 (83)

88 (89)

89 (91)

88 (91)

  

91 (92)

  
 

mouse

83 (58)

83 (88)

83 (87)

81 (89)

  

88 (96)

  

CEACAM18

human

76 (58)

77 (60)

72 (57)

73 (62)

   

69 (52)

 
 

mouse

46 (47)

71 (66)

65 (55)

68 (60)

   

51 (35)

 

CEACAM19

human

83 (66)

82 (78)

     

81 (69)

78 (65)

 

mouse

51 (41)

75 (68)

     

76 (59)

75 (59)

CEACAM20

human

86 (76)

79 (57)

78 (62)

79 (68)

76 (65)

77 (70)

 

72 (56)

65 (41)

 

mouse

59 (23)

65 (35)

69 (53)

71 (54)

72 (64)

72 (66)

 

66 (51)

56 (40)

  1. The nucleotide and amino acid sequences of leader (L), IgV-like domain (N1, N2), IgC-like domain (A1, A2, B1, B2), transmembrane domain (TM) and combined cytoplasmic domain exons (Cyt) were compared pairwise using the ClustalW software (Weight Matrix BLOSOM). The degree of identity is indicated in % (amino acid sequence identity in brackets).