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Table 1 Relationship between dog CEA family members and human and mouse orthologs

From: Species-specific evolution of immune receptor tyrosine based activation motif-containing CEACAM1-related immune receptors in the dog

  ortholog L N1 A1 B1 A2 B2 N2 TM Cyt
CEACAM1 human 64 (47) 73 (56) 79 (68) 83 (76) 75 (60)    63 (48) 79 (61)
  mouse 57 (47) 62 (42) 74 (64) 80 (66) 71 (58)    67 (64) 78 (65)
CEACAM16 human 86 (83) 88 (89) 89 (91) 88 (91)    91 (92)   
  mouse 83 (58) 83 (88) 83 (87) 81 (89)    88 (96)   
CEACAM18 human 76 (58) 77 (60) 72 (57) 73 (62)     69 (52)  
  mouse 46 (47) 71 (66) 65 (55) 68 (60)     51 (35)  
CEACAM19 human 83 (66) 82 (78)       81 (69) 78 (65)
  mouse 51 (41) 75 (68)       76 (59) 75 (59)
CEACAM20 human 86 (76) 79 (57) 78 (62) 79 (68) 76 (65) 77 (70)   72 (56) 65 (41)
  mouse 59 (23) 65 (35) 69 (53) 71 (54) 72 (64) 72 (66)   66 (51) 56 (40)
  1. The nucleotide and amino acid sequences of leader (L), IgV-like domain (N1, N2), IgC-like domain (A1, A2, B1, B2), transmembrane domain (TM) and combined cytoplasmic domain exons (Cyt) were compared pairwise using the ClustalW software (Weight Matrix BLOSOM). The degree of identity is indicated in % (amino acid sequence identity in brackets).