Table 1 GO categories listed for domain families with statistically significant bias (p-value < 0.01) with respect to increasing, decreasing and stable individual spacers.
From: Long-term trends in evolution of indels in protein sequences
Decreasing | Stable | Increasing | GO annotation | P-value |
|---|---|---|---|---|
6 (9.8) | 47 (64.9) | 38 (16.3) | transferase activity, transferring glycosyl groups | 0.0000 |
12 (11.2) | 52 (74.2) | 40 (18.7) | replicative cell aging | 0.0000 |
25 (11.7) | 58 (77.7) | 26 (19.6) | endoplasmic reticulum membrane | 0.0000 |
24 (20.6) | 112 (136.9) | 56 (34.5) | positive regulation of cell proliferation | 0.0001 |
0 (11.7) | 93 (77.7) | 16 (19.6) | ubiquitin cycle | 0.0005 |
14 (32.1) | 231 (213.2) | 54 (53.7) | membrane fraction | 0.0029 |
5 (8.6) | 70 (57.1) | 5 (14.4) | chemotaxis | 0.0052 |
0 (8.9) | 66 (59.2) | 17 (14.9) | ubiquitin-dependent protein catabolism | 0.0068 |
4 (13.5) | 91 (89.9) | 31 (22.6) | mitosis | 0.0074 |
30 (33.5) | 205 (222.5) | 77 (56) | transcription | 0.0082 |
2 (8.2) | 66 (54.2) | 8 (13.6) | protein folding | 0.0084 |
4 (14.9) | 111 (99.1) | 24 (25) | G-protein coupled receptor protein signaling pathway | 0.0089 |