Figure 7From: Recurrent adenylation domain replacement in the microcystin synthetase gene clusterDiscordant phylogenetic relationships between the McyB1 and McyC condensation and adenylation domains. (a) A maximum-likelihood tree based on the McyB1 and McyC condensation domains (C) reflecting separate evolutionary history for these two condensation domains indicating the chirality of the amino acid at the donor site of the condensation domain (-lnL = 21740.48206). (b) A maximum-likelihood tree based on the McyB1 and McyC adenylation domains (A), from A3–A8, showing intermixed cluster of McyB1 and McyC adenylation reflecting a more recent evolutionary history characterized by periods of replacement through recombination leading to domain replacement (-lnL = 10308.24462).Back to article page