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Table 1 Growth of control and pifithrin-α treated animals during limb regeneration

From: Urodele p53 tolerates amino acid changes found in p53 variants linked to human cancer

Animal

Treatment

Lenght of the pre-amputated animals

Lenght of the animals 24 days post-treatment and amputation

Growth Ratio (pre-amp/post-amp)

1

Control DMSO

3.5 cm

4 cm

0.88

2

Control DMSO

3.5 cm

3.9 cm

0.9

3

Control DMSO

3.0 cm

3.5 cm

0.86

4

Pifithrin-α 5 μM

3.0 cm

3.5 cm

0.86

5

Pifithrin-α 5 μM

3.2 cm

3.7 cm

0.86

6

Pifithrin-α 5 μM

3.0 cm

3.4 cm

0.88

  1. no significant difference in growth observed between control and pifithrin treated animals (p > 0.05)