Figure 1
From: Urodele p53 tolerates amino acid changes found in p53 variants linked to human cancer
Effect of pifithrin-α on limb regeneration. (A & E) Controls treated daily with DMSO. (B-D & F-G) Pifithrin-α treated animals (5 μM pifithrin-α, added freshly diluted everyday). Limbs in panels A-D were amputated distally in the middle of the zeugopod and limbs in panels E-G were amputated proximally through the middle of the stylopod (see dotted lines in panels A & E for amputation levels).