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Figure 11 | BMC Evolutionary Biology

Figure 11

From: Ancient intron insertion sites and palindromic genomic duplication evolutionally shapes an elementally functioning membrane protein family

Figure 11

The short region of the alignment of 115 AA sequences illustrates an exclusively conserved intron insertion site among the tunicate and vertebrate GIRK group. Alignment: HR-115IRK-GMVEATGM The region corresponded to 21 amino acids from V303 and M323 in the C-terminal domain of human Kcnj5 (GIRK4). Glycine colored by green indicates the intron insertion site between the first and second nucleotides in the codon (phase 1 intron). In other group, the insertion site was not conserved in spite of the conserved amino acid residue in some genes.

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