Analysis of septins across kingdoms reveals orthology and new motifs

Pan, Fangfang; Malmberg, Russell L; Momany, Michelle

doi:10.1186/1471-2148-7-103

BMC Ecology and Evolution

Table 1 Septin and septin-like sequences analyzed.

From: Analysis of septins across kingdoms reveals orthology and new motifs

GI*	Name in Paper^†	Proposed Name*	Alias^‡	Clade/Species^§		Group^¶	G^\|\|	C**
gi\|2244629	AbiSep	/	sepA	F	Agaricus bisporus	Tr	+	+
gi\|31198659	AgaHyp1	Pnut		A	Anopheles gambiae	2B	+	+
gi\|31202059	AgaHyp2	Sep2		A	Anopheles gambiae	1B	+	+
gi\|31206631	AgaHyp3	Sep1		A	Anopheles gambiae	2B	+	+
gi\|31204715	AgaHyp4	Sep4		A	Anopheles gambiae	2B	+	+
gi\|13398364	AniAspA	Cdc11		F	Aspergillus nidulans	3	+	+
gi\|1791305	AniAspB	Cdc3		F	Aspergillus nidulans	2A	+	+
gi\|34811845	AniAspC	Cdc12		F	Aspergillus nidulans	4	+	+
gi\|34148975	AniAspD	Cdc10		F	Aspergillus nidulans	1A	+	-
gi\|34811843	AniAspE	AspE		F	Aspergillus nidulans	5	+	-
gi\|45645169	BtaCdc10	/		A	Bos taurus	2B	+	+
gi\|39580970	CbrHyp1	Unc59b	CBG20268	A	Caenorhabditis briggsae	2B	+	+
gi\|39589843	CbrHyp2	Unc61	CBG04550	A	Caenorhabditis briggsae	1B	+	+
gi\|39584450	CbrHyp3	Unc59a	CBG19777	A	Caenorhabditis briggsae	2B	+	+
gi\|17509405	CelUnc59	/		A	Caenorhabditis elegans	2B	+	+
gi\|32566810	CelUnc61	/		A	Caenorhabditis elegans	1B	+	+
gi\|729090	CalCdc3	/		F	Candida albicans	2A	+	+
gi\|729064	CalCdc10	/		F	Candida albicans	1A	+	-
gi\|21435770	CalCdc11	/		F	Candida albicans	3	+	+
gi\|21435778	CalCdc12	/		F	Candida albicans	4	+	+
gi\|21435802	CalSep7	Shs1	SHS1	F	Candida albicans	3	+	+
gi\|46442449	CalSpr28	/		F	Candida albicans	3	+	-
gi\|46444553	CalSpr3	/		F	Candida albicans	4	+	+
gi\|50286825	CglHyp1	Cdc3		F	Candida glabrata	2A	+	+
gi\|50284895	CglHyp2	Cdc12a		F	Candida glabrata	4	+	+
gi\|50288449	CglHyp3	Cdc10		F	Candida glabrata	1A	+	-
gi\|50289749	CglHyp4	Cdc12b		F	Candida glabrata	4	+	+
gi\|50287113	CglHyp5	Cdc11		F	Candida glabrata	3	+	+
gi\|50288341	CglHyp6	Shs1		F	Candida glabrata	3	+	+
gi\|50291973	CglHyp7	Spr3		F	Candida glabrata	4	+	+
gi\|50286937	CglHyp8	Spr28		F	Candida glabrata	3	+	+
gi\|18476091	CimSep1	Cdc11		F	Coccidioides immitis	3	+	+
gi\|24637104	CimSep2	Cdc3		F	Coccidioides immitis	2A	+	+
gi\|24637108	CimSep3	Cdc10		F	Coccidioides immitis	1A	+	-
gi\|24473756	CimSep4	AspE		F	Coccidioides immitis	5	+	-
gi\|50257384	CneHyp1	Cdc3		F	Cryptococcus neoformans	2A	+	+
gi\|50259101	CneHyp2	Cdc12		F	Cryptococcus neoformans	4	+	+
gi\|50258769	CneHyp3	Cdc10		F	Cryptococcus neoformans	1A	+	-
gi\|50257720	CneHyp4	Cdc11		F	Cryptococcus neoformans	3	+	+
gi\|50260201	CneHyp5	AspE		F	Cryptococcus neoformans	5	+	-
gi\|41055580	DreHyp1	Sept7	zgc:56383	A	Danio rerio	2B	+	+
gi\|32822794	DreHyp2	Sept8	wu:fb22a03	A	Danio rerio	1B	+	+
gi\|41152396	DreHyp4	Sept5	zgc:73218	A	Danio rerio	2B	+	+
gi\|40538786	DreMsf	Sept9	MLL septin-like fusion	A	Danio rerio	1A	+	-
gi\|45709377	DreNedd5	Sept2	zgc:63587	A	Danio rerio	2B	+	+
gi\|47086783	DreSept6	/	zgc:66071	A	Danio rerio	1B	+	+
gi\|50420949	DhaHyp1	Cdc3		F	Debaryomyces hansenii	2A	+	+
gi\|50426961	DhaHyp2	Cdc12		F	Debaryomyces hansenii	4	+	+
gi\|50425027	DhaHyp3	Cdc10		F	Debaryomyces hansenii	1A	+	-
gi\|50426163	DhaHyp4	Spr3		F	Debaryomyces hansenii	4	+	+
gi\|50418421	DhaHyp5	Cdc11		F	Debaryomyces hansenii	3	+	+
gi\|50414330	DhaHyp6	Shs1		F	Debaryomyces hansenii	3	+	+
gi\|730352	DmePnut	/		A	Drosophila melanogaster	2B	+	+
gi\|17647925	DmeSep1	/		A	Drosophila melanogaster	2B	+	+
gi\|17738071	DmeSep2	/		A	Drosophila melanogaster	1B	+	+
gi\|24642597	DmeSep4	/	CG9699	A	Drosophila melanogaster	2B	+	+
gi\|21356243	DmeSep5	/		A	Drosophila melanogaster	1B	+	+
gi\|38047705	DyaSep2	/		A	Drosophila yakuba	Tr	-	+
gi\|19075150	EcuSep1	Spr3a	ECU01_1370	M	Encephalitozoon cuniculi	4	+	+
gi\|19074995	EcuSep2	Spr3b	ECU11_1950	M	Encephalitozoon cuniculi	4	+	+
gi\|19173204	EcuSep3	Cdc11	ECU09_0820	M	Encephalitozoon cuniculi	3	+	-
gi\|45198629	EgoHyp1	Cdc3		F	Eremothecium gossypii	2A	+	+
gi\|45190841	EgoHyp2	Cdc12		F	Eremothecium gossypii	4	+	+
gi\|45184824	EgoHyp3	Cdc10		F	Eremothecium gossypii	1A	+	-
gi\|45191046	EgoHyp4	Cdc11		F	Eremothecium gossypii	3	+	+
gi\|45199089	EgoHyp5	Spr3		F	Eremothecium gossypii	4	+	+
gi\|45201271	EgoHyp6	Spr28		F	Eremothecium gossypii	3	+	-
gi\|45185071	EgoHyp7	Shs1		F	Eremothecium gossypii	3	+	+
gi\|14041182	GcySep1	/		A	Geodia cydonium	2B	+	+
gi\|29249771	Gla	/		P	Giardia lamblia	Slk	-	-
gi\|46121875	GzeHyp1	Cdc3		F	Gibberella zeae	2A	+	+
gi\|46126005	GzeHyp2	Cdc12		F	Gibberella zeae	4	+	+
gi\|46135811	GzeHyp3	Cdc11		F	Gibberella zeae	3	+	+
gi\|46123315	GzeHyp4	Cdc10		F	Gibberella zeae	1A	+	-
gi\|46128665	GzeHyp5	AspE		F	Gibberella zeae	5	+	-
gi\|46122029	GzeHyp6	AspE2		F	Gibberella zeae	5	+	-
gi\|46139179	GzeHyp7	/		F	Gibberella zeae	Slk	+	+
gi\|16604248	HsaSept1	/		A	Homo sapiens	2B	+	+
gi\|4758158	HsaSept2	/	Nedd5, Pnutl3, Diff6, KIA0158	A	Homo sapiens	2B	+	+
gi\|22035572	HsaSept3	/		A	Homo sapiens	1A	+	-
gi\|4758942	HsaSept4	/	H5, Bradion, Pnutl2, ARTS, MART, hCDCrel-2, Septin-M	A	Homo sapiens	2B	+	+
gi\|9945439	HsaSept5	/	Pnutl, hCDCrel-1	A	Homo sapiens	2B	+	+
gi\|22035577	HsaSept6	/	Sept2, KIA0128	A	Homo sapiens	1B	+	+
gi\|4502695	HsaSept7	/	hCdc10	A	Homo sapiens	2B	+	+
gi\|41147049	HsaSept8	/	KIA0202	A	Homo sapiens	1B	+	+
gi\|6683817	HsaSept9	/	AF17q25, MSF, SepD1, Ov/Br septin, Pnutl4, KIA0991	A	Homo sapiens	1A	+	-
gi\|18088518	HsaSept10	/	Sep1-like	A	Homo sapiens	1B	+	+
gi\|8922712	HsaSept11	/	FLJ10849	A	Homo sapiens	1B	+	+
gi\|23242699	HsaSept12	/	FLJ25410	A	Homo sapiens	1A	+	-
gi\|113418512	HsaSept13	/		A	Homo sapiens	2B	+	+
gi\|50306547	KlaHyp1	Cdc3		F	Kluyveromyces lactis	2A	+	+
gi\|50309827	KlaHyp2	Cdc12		F	Kluyveromyces lactis	4	+	+
gi\|50311269	KlaHyp3	Cdc10		F	Kluyveromyces lactis	1A	+	-
gi\|50303889	KlaHyp4	Spr3		F	Kluyveromyces lactis	4	+	+
gi\|50304439	KlaHyp5	Cdc11		F	Kluyveromyces lactis	3	+	+
gi\|50311965	KlaHyp6	Shs1		F	Kluyveromyces lactis	3	+	+
gi\|50311291	KlaHyp7	Spr28		F	Kluyveromyces lactis	3	+	-
gi\|13358928	MfaHyp1	Sept5		A	Macaca fascicularis	2B	+	+
gi\|38110101	MgrHyp1	Cdc3		F	Magnaporthe grisea	2A	+	+
gi\|38106951	MgrHyp2	Cdc12		F	Magnaporthe grisea	4	+	+
gi\|38109157	MgrHyp3	Cdc10		F	Magnaporthe grisea	1A	+	-
gi\|38100755	MgrHyp4	Cdc11		F	Magnaporthe grisea	3	+	+
gi\|38100224	MgrHyp5	AspE		F	Magnaporthe grisea	5	+	-
gi\|38110686	MgrHyp6	AspE2		F	Magnaporthe grisea	5	+	-
gi\|6453576	MciSepA	/	sepA	F	Mucor circinelloides	4	+	+
gi\|8567344	MmuSept1	/	Diff6	A	Mus musculus	2B	+	+
gi\|6754816	MmuSept2	/	Nedd5	A	Mus musculus	2B	+	+
gi\|6755468	MmuSept3	/	mKIAA0991, G septin	A	Mus musculus	1A	+	-
gi\|6755120	MmuSept4	/	M-Septin, H5	A	Mus musculus	2B	+	+
gi\|6685763	MmuSept5	/	Cdcrel-1, Pnutl1	A	Mus musculus	2B	+	+
gi\|20178348	MmuSept6	/		A	Mus musculus	1B	+	+
gi\|9789726	MmuSept7	/	Cdc10	A	Mus musculus	2B	+	+
gi\|39930477	MmuSept8	/	mKIAA0202	A	Mus musculus	1B	+	+
gi\|28204888	MmuSept9	/	Sint1, E-septin, SLP-a	A	Mus musculus	1A	+	-
gi\|26345492	MmuSept10a	/		A	Mus musculus	1B	+	+
gi\|38082026	MmuSept10b	/	1700016K13Rik	A	Mus musculus	1B	+	+
gi\|26324430	MmuSept11	/	D5Ertd606e	A	Mus musculus	1B	+	+
gi\|20891621	MmuSept12	/	4933413B09Rik	A	Mus musculus	1A	+	-
gi\|32417050	NcrHyp1	Cdc3		F	Neurospora crassa	2A	+	+
gi\|32404966	NcrHyp2	Cdc12		F	Neurospora crassa	4	+	+
gi\|32404320	NcrHyp3	Cdc10		F	Neurospora crassa	1A	+	-
gi\|32422439	NcrHyp4	Cdc11		F	Neurospora crassa	3	+	+
gi\|32417420	NcrHyp5	AspE		F	Neurospora crassa	5	+	-
gi\|32411577	NcrHyp6	AspE2		F	Neurospora crassa	5	+	-
gi\|32411845	NcrHyp7			F	Neurospora crassa	Slk	-	-
gi\|5725417	PbrPbs1	Cdc11	pcd1	F	Pyrenopeziza brassicae	3	+	+
gi\|34859284	RnoSept1	/	LOC293507	A	Rattus norvegicus	2B	+	+
gi\|16924010	RnoSept2	/		A	Rattus norvegicus	2B	+	+
gi\|9507085	RnoSept3	/	G-septin	A	Rattus norvegicus	1A	+	-
gi\|32423788	RnoSept4	/	LOC287606, EG3RVC, EG3-1RVC	A	Rattus norvegicus	2B	+	+
gi\|16758814	RnoSept5	/	Gp1bb, CDCrel-1, PNUTL1ai, CDCrel-1AI	A	Rattus norvegicus	2B	+	+
gi\|34932994	RnoSept6	/	LOC298316	A	Rattus norvegicus	1B	+	+
gi\|12018296	RnoSept7	/	Cdc10	A	Rattus norvegicus	2B	+	+
gi\|34870727	RnoSept8	/	LOC303135	A	Rattus norvegicus	1B	+	+
gi\|13929200	RnoSept9	/	Slpa, E-Septin	A	Rattus norvegicus	1A	+	-
gi\|34882181	RnoSept10a	/	LOC309891	A	Rattus norvegicus	1B	+	+
gi\|34872099	RnoSept10b	/	LOC288622	A	Rattus norvegicus	1B	+	+
gi\|34876531	RnoSept11	/	LOC305227	A	Rattus norvegicus	1B	+	+
gi\|34868752	RnoSept12	/	LOC363542	A	Rattus norvegicus	1A	+	-
gi\|6323346	SceCdc3	/		F	Saccharomyces cerevisiae	2A	+	+
gi\|6319847	SceCdc10	/		F	Saccharomyces cerevisiae	1A	+	-
gi\|6322536	SceCdc11	/		F	Saccharomyces cerevisiae	3	+	+
gi\|6321899	SceCdc12	/		F	Saccharomyces cerevisiae	4	+	+
gi\|6319976	SceShs1	/	Sep7	F	Saccharomyces cerevisiae	3	+	+
gi\|6320424	SceSpr28	/		F	Saccharomyces cerevisiae	3	+	+
gi\|6321496	SceSpr3	/		F	Saccharomyces cerevisiae	4	+	+
gi\|19115666	SpoSpn1	/		F	Schizosaccharomyces pombe	2A	+	+
gi\|19114071	SpoSpn2	/		F	Schizosaccharomyces pombe	1A	+	-
gi\|13638491	SpoSpn3	/		F	Schizosaccharomyces pombe	3	+	+
gi\|19114478	SpoSpn4	/		F	Schizosaccharomyces pombe	4	+	+
gi\|19114952	SpoSpn5	/		F	Schizosaccharomyces pombe	3	+	+
gi\|19075714	SpoSpn6	/	SPCC584.09	F	Schizosaccharomyces pombe	4	+	+
gi\|15214304	SpoSpn7	/	SPBC19F8.01c	F	Schizosaccharomyces pombe	3	+	-
gi\|20177379	SdoSeptl	/		A	Suberites domuncula	2B	+	+
gi\|33302067	UmaCdc10	/		F	Ustilago maydis	1A	+	-
gi\|46099680	UmaHyp1	Cdc3		F	Ustilago maydis	2A	+	+
gi\|46099269	UmaHyp2	Cdc12		F	Ustilago maydis	4	+	+
gi\|46099354	UmaHyp3	Cdc11	Sep3	F	Ustilago maydis	3	+	+
gi\|34784614	XlaHyp1	Sept12	MGC68931	A	Xenopus laevis	1A	+	-
gi\|12003372	XlaSeptA	Sept2		A	Xenopus laevis	2B	+	+
gi\|50551445	YliHyp1	Cdc3		F	Yarrowia lipolytica	2A	+	+
gi\|50549207	YliHyp2	Cdc10		F	Yarrowia lipolytica	1A	+	-
gi\|50551749	YliHyp3	Cdc12		F	Yarrowia lipolytica	4	+	+
gi\|50553330	YliHyp4	Cdc11a		F	Yarrowia lipolytica	3	+	+
gi\|50549013	YliHyp5	Spr28		F	Yarrowia lipolytica	3	+	+
gi\|50547965	YliHyp6	Cdc11b		F	Yarrowia lipolytica	3	+	+
gi\|50557032	YliHyp7	Spr3		F	Yarrowia lipolytica	4	+	+
gi\|13940377	ZroCDC	/	er001-c	F	Zygosaccharomyces rouxii	Tr	+	-

* Genbank identification numbers.
† The first three letters represent genus and species names. The last letters represent current septin protein name.
* Proposed names based on first- or best-characterized septin in each clade.
‡ Alias designations from Genbank and [27, 28]
§ A represents animals; F represents fungi; M represents microsporidia.
¶ Group names are assigned according to phylogenetic analysis shown in Figure 2. tr, truncated; slk, septin-like.
|| Presence of full length GTP_CDC detected by the SMART program.
** Predicted coiled-coil at C terminus.

Back to article page

ISSN: 2730-7182

Contact us

General enquiries: journalsubmissions@springernature.com