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Table 2 The effects of codon usage bias on LRTs (n = 29)

From: Tracking the connection between evolutionary and functional shifts using the fungal lipase/feruloyl esterase A family

  

Model

  

F equal

F3×4

F codon

Estimates under model A

 

p0 = 0.427, p1 = 0.241

(p2 + p3) = 0.330

ω2 = 11.182

p0 = 0.452, p1 = 0.170

(p2 + p3) = 0.376

ω2 = 999

p0 = 0.469, p1 = 0.157

(p2 + p3) = 0.372

ω2 = 999

Estimates under M1a

 

p0 = 0.627, p1 = 0.372

ω0 = 0.193

p0 = 0.711, p1 = 0.288

ω0 = 0.126

p0 = 0.730, p1 = 0.269

ω0 = 0.113

Estimates under model A (ω2 = 1)

 

p0 = 0.437, p1 = 0.259 (p2 + p3) = 0.302

ω0 = 0.187

p0 = 0.480, p1 = 0.189 (p2 + p3) = 0.329

ω0 = 0.121

p0 = 0.505, p1 = 0.178 (p2 + p3) = 0.316

ω0 = 0.107

2Δl

Test 1:

35.44

53.78

54.38

 

Test 2:

19.98

28.22

27.89

  1. Note: Branch-site model A was compared to site model M1a and model A with ω2 fixed to 1 for test 1 and 2, respectively. All tests are significant at 1%; with df = 2 and df = 1 for tests 1 and 2, respectively.