|
Archaea_only (131 sequences)
|
|
Ribosomal proteins
|
25
|
Involved in catalyzing mRNA-directed protein synthesis
|
|
RNA polymerase
|
20
|
Catalyse the DNA dependent polymerisation of RNA
|
|
Translation initiation factor
|
12
|
Required for maximal rate of protein biosynthesis, in directing ribosome to proper start state of translation
|
|
DNA polymerase
|
5
|
Required in replication of DNA
|
|
Diphthamide_syn
|
5
|
Putative diphthamide synthesis protein
|
|
Bacteria_only (1102 sequences)
|
|
Sulfotransferases
|
67
|
Responsible for the transfer of sulphate groups to specific compounds
|
|
Tubulin
|
35
|
Major component of microtubules, involved in polymer formation
|
|
DAGAT
|
23
|
The enzyme diacylglycerol acyltransferase involved in the catalysis of terminal step of triacylglycerol
|
|
Carb_anhydrase
|
23
|
Carbonic anhydrase, catalyze reversible hydration of carbon dioxide
|
|
2OG-FeII_Oxy
|
21
|
2-oxoglutarate and Fe(II)-dependent oxygenase superfamily
|
|
Ribosomal protein
|
17
|
Involved in catalyzing mRNA-directed protein synthesis
|
|
Eukaryota (2928 sequences)
|
|
K_tetra
|
120
|
K+ channel cytoplasmic tetramerisation domain
|
|
Ocular_alb
|
113
|
X-linked disorder characterized by severe impairment of visual acuity, retinal hypopigmentation and the presence of macromelanosomes
|
|
CH
|
109
|
Calponin homology domain, found in both cytoskeletal and signal transduction protein
|
|
Histone
|
68
|
Core Histone H2A/H2B/H3/H4, involved in histone-histone and histone-DNA interactions
|
|
7 tm_3
|
65
|
7 transmembrane receptor (metabotropic glutamate family), coupled to G-proteins and stimulate the inositol phosphate/Ca2+ intracellular signalling pathway
|
|
Actin
|
62
|
Involved in formation of filament, major component of cytoskeleton
|
|
Fork_head
|
59
|
A transcription factor that promotes terminal rather than segmental development, involved in early developmental decisions of cell fates during embryogenesis
|
|
UQ_con
|
59
|
Ubiquitin-conjugating enzyme, involved in catalytic activity or assist in poly-ubiquitin chain formation
|
|
Metazoa (1362 sequences)
|
|
Zf-C4
|
88
|
DNA binding domain of a nuclear hormone receptor
|
|
PID
|
67
|
Phosphotyrosine interaction domain
|
|
RA
|
51
|
Ras association domain
|
|
sema
|
48
|
The Sema domain occurs in semaphorins, which are a large family of secreted and transmembrane proteins, some of which function as repellent signals during axon guidance
|
|
Ets
|
37
|
Erythroblast transformation specific domain, required for induction of erythroblastosis
|
|
Wnt
|
25
|
Role in intercellular communication, possible role in central nervous system
|
|
T-box
|
24
|
Perform DNA-binding and transcriptional activation/repression roles
|
|
Chordata (470 sequences)
|
|
Connexin
|
22
|
Gap junction protein
|
|
Interferon
|
19
|
Produce antiviral and antiproliferative responses in cells
|
|
Protocadherin
|
17
|
Cadherin-related molecules in central nervous system
|
|
MHC_II_alpha
|
15
|
Related with cell-mediated immune responses
|
|
Fn2
|
14
|
Fibronectin type II domain, involved in a number of important functions e.g., wound healing; cell adhesion; blood coagulation; cell differentiation and migration; maintenance of the cellular cytoskeleton; and tumour metastasis
|
|
Mammalia (146 sequences)
|
|
Gag_p10
|
21
|
The p10 or matrix protein (MA) is associated with the virus envelope glycoproteins in most mammalian retroviruses and may be involved in virus particle assembly, transport and budding
|
|
GP41
|
16
|
The GP41 subunit of the envelope protein complex mediates membrane fusion during viral entry
|
|
Bim_N
|
11
|
Bim protein N terminus, essential initiators of apoptotic cell death
|
|
Primates (21 sequences)
|
|
SPAN-X
|
14
|
Human sperm proteins associated with the nucleus and mapped to the X chromosome, they are cancer-testis antigens.
|
|
Homo sapiens (120 sequences)
|
|
GP120
|
9
|
Envelope glycoprotein GP120
|
|
BAGE
|
5
|
B melanoma antigen family
|
