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Table 3 Evolutionary origin of Pfam-A families at different eukaryotic nodes

From: Tracing the origin of functional and conserved domains in the human proteome: implications for protein evolution at the modular level

Node of origin Number of Pfam-A families with remote homologs at
  Single node Multiple node Total
Eukaryota 667 334 1001
Metazoa 255 115 370
Chordata 154 64 218
Mammalia 54 18 72
Primates 4 3 7
Homo sapiens 44 0 44