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Figure 5 | BMC Evolutionary Biology

Figure 5

From: Tracing the origin of functional and conserved domains in the human proteome: implications for protein evolution at the modular level

Figure 5

Grouping of Pfam-A families according to the number of nodes (where remote homologs are found along the lineage) associated with it. (A) Distribution of different groups of Pfam-A families is plotted in the left axis with decaying nature best approximated by power-law with Y ~ X-1.7 (R2 = 0.95), compared to an exponential, linear or logarithmic function, whereas average numbers of human domains in each group of Pfam-A families are plotted in the right axis with exponentially rising nature with Y = 3.6 × e-0.7X (R2 = 0.97). (B) Distribution of sorted Pfam-A families by average percentage sequence identity of domains within same family (families with number of domains less than 10 are excluded from this graph) in different groups. The maximum probable range of each curve is the more flattened portion.

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