Figure 2

Transposon inverted and direct repeats. A: the complete sequence of SmTRC1 TIR is shown in this panel. Dots represent the transposon sequence not shown in the figure. B: blue boxes show direct repeats flanking S. mansoni and other animal TIRs (in gray). Only part of the S. mansoni TIR is represented in the figure. The dots represent the transposon sequence not shown in the figure. C: examples of target-site duplication created upon SmTRC1 insertion. Examples of alignments of sequences flanking SmTRC1 insertions (S-0000026, S-0000464 and S-0000144) with paralogous genomic sequences lacking transposon insertions (BH202398.1, BN000802.1 and AL620357.1) that were found in the S. mansoni public sequences database. The paralogous "gap" sequence (marked as –) presumably corresponds to the genomic target sequence before a transposon insertion event. Blue boxes indicate the target-site duplication in the flanking sequence. The number on the side of each sequence represents the supercontig from which it was derived (in the case of transposon inserted sequences) or GenBank accession numbers (in the case of paralogous sequences). D: TIR sequences from diverse CACTA superfamily animal and plant elements. The regions with high and medium levels of identity among the sequences are shown as black and gray columns, respectively.