Skip to main content
Figure 2 | BMC Evolutionary Biology

Figure 2

From: Insights into the evolution of the ErbB receptor family and their ligands from sequence analysis

Figure 2

Consensus sequences for the mammalian ligands. Alignment was generated in ClustalX [60]. To minimize errors in amino acid sequence from the DNA sequences used in the analysis, a conserved residue was called conserved if it was in at least 75% of the sequences for an individual ligand. In the alignment, gaps are denoted by a dash (-) and non-conserved residues are indicated by an X. Reverse text (white text on black background) denotes residues that are at least 75% conserved among the different ligands, with grey shaded text (black text on grey background) denoting residues that are different at these conserved positions. Shown for comparison at the bottom is the sequence of human EGF and numbering for the mature ligand.

Back to article page