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Table 9 Clusters with mammalian sequences only

From: Coiled-coil protein composition of 22 proteomes – differences and common themes in subcellular infrastructure and traffic control

Cluster size

(# of sequences)

Max. edge

(P-score)

protein family

putative function/site of action

organism

51

<E-40

Keratin type II

IF, cytoskeletal (cytokeratin), hair

H.s., M.m.

45

5.0E-7

Keratin type I (hair keratin)

IF, cuticular/hair

H.s., M.m.

32

4.2E-7

Keratin type I

IF, cytoskeletal (cytokeratin), root sheeth

H.s., M.m.

31

9.2E-7

Keratin type II

IF, cytoskeletal (cytokeratin), hair

H.s., M.m.

24

3.9E-7

Keratin type I (hair keratin)

IF, cuticular/hair

H.s., M.m.

18

1.4E-14

Neurofilaments (Desmin, Internexin, Peripherin, Vimentin)

IFs

H.s., M.m.

13

1.2E-25

Interferon-induced guanylate-binding proteins

 

H.s., M.m.

10

1.9E-8

Plectin, Desmoplakin, Periplakin, Envoplakin

 

H.s., M.m.

  1. Numbers include "bridge" sequences qualifying for more than one cluster. Only clusters represented by at least 10 sequences are listed. See Table S16 for protein details on clusters smaller than 10. For species name abbreviations, see Table 1.