Table 6 Eukaryotic clusters
Cluster size (# of sequences) | Max. edge (P-score) | protein family | putative function/site of action | organisms represented |
|---|---|---|---|---|
94 | 5.4E-10 | Myosin heavy chain | actin motor protein (muscle, cytoskeleton) | A.t., C.e., D.m., H.s., M.m., O.s., S.c., S.p. |
27 | 1.5E-36 | Kinesin heavy chain (KCBP, KIFC) | MT motor protein (cytoskeleton) | A.t., C.e., D.m., H.s., M.m., O.s., S.c., S.p. |
21 | 1.1E-35 | Kinesin heavy chain (Cmet/Cana, MKRPs, NACK/HINKEL) | MT motor protein (cytoskeleton) | A.t., D.m., H.s., M.m., O.s., S.p. |
17 | 1.2E-7 | Structural maintenance of chromosomes 5–6/RAD18 | DNA repair (chromatin) | A.t., C.e., D.m., H.s., M.m., O.s., S.c., S.p. |
12 | 5.0E-7 | Kinases (GIN4, MET) | signal transduction | A.t., D.m., H.s., O.s., S.c. |
11 | <E-40 | RAD50 (eukaryotic) | DNA repair | A.t., C.e., D.m., H.s., M.m., O.s., S.c., S.p. |
11 | 1.2E-7 | Retinoblastoma-associated protein, RING finger protein 20 | E3 Ubi. ligase for H2B histone modification (nuclear)? | A.t., C.e., D.m., H.s., M.m., O.s., S.c, S.p. |