Coiled-coil protein composition of 22 proteomes – differences and common themes in subcellular infrastructure and traffic control

Table 2 Clustering results

Annotation	# sequences	Species
Myosins	56	A.t., C.e., D.m., H.s., M.m., O.s., S.c., S.p.
SMCs	13	A.f., A.tu., B.b., B.s., C.v., H.s., M.g., M.j., M.m., M.t., S.c., S.sp., T.a.
Laminins	10	D.m., H.s., M.m.
ROCK	9	C.e., D.m., H.s., M.m.
ELKS/ERC1	7	H.s., M.m.
SLAP	5	H.s., M.m.
Kinectin	5	H.s., M.m.
Periplakin	5	H.s., M.m.
DOC1/FILIP	5	H.s.
C-Nap	5	D.m., H.s., M.m.
CASP/CDP	4	H.s., M.m.
CENP-F	4	H.s., M.m.
Lamins	4	H.s., M.m.
Hypothetical	4	C.e.
Unknown	4	A.t., O.s., S.p.
Unknown	4	A.t., O.s.

Largest clusters identified in a pilot analysis using all prokaryotic long coiled-coil proteins and eukaryotic proteins with coiled-coil domains longer than 250 amino acids or more than 60% coverage. Only clusters with four or more members are listed. ROCK, Rho-associated coiled-coil containing kinase [114]; ELKS/ERC1, Rab6-interacting protein [115], SLAP, sarcolemmal-associated protein [116]; DOC1, downregulated in ovarian cancer 1 [117]; CENP-F, centromer protein F [118]. For species name abbreviations, see Table 1.

ISSN: 2730-7182