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Table 3 Results of randomizations controlling for breadth of expression. The "Aug" (Augmented) data set is that containing the two ligand -receptor sets nominated by Cooper [20]. Bin size indicates the span of breadths of expression considered to be the same in the randomizations. Bin size one implies that only genes of the same breadth were switched with each other. Distances are measured in Mb. P-values are estimated by comparison of observed data with expectations obtained from randomised genomes.

From: Unusual linkage patterns of ligands and their cognate receptors indicate a novel reason for non-random gene order in the human genome

Data set

Bin size

N

# on same chr (observed)

# on same chr (expected)

P

Mean dist. (observed)

Mean dist. (expected)

P

Aug

1

267

25

14.18

0.011

63.47

55.22

0.741

Aug

5

267

25

14.14

0.01

63.47

55.77

0.705

Non-Aug

1

265

23

14.09

0.027

64.58

56.25

0.731

Non-Aug

5

265

23

13.8

0.013

64.58

55.47

0.752