Selected horizontally transferred genes/operons | T. thermophilus Protein ID | D. radiodurans Protein ID | Comment |
---|---|---|---|
Xenologous gene displacement | |||
Ribosomal protein L15 (COG0200) | TTC1309 | DR2115 | Proteobacterial affinity of DR; Affinity to Thermatoga/Aquifex/other Gram-positive bacteria in TT |
Ribosomal protein L30/L7E (COG1841) | TTC1310 | DR2114 | Thermatogales/Aquifecales version in TT, affinity to other bacteria in DR |
Thiamine biosynthesis protein ThiC (COG0422) | TTC0319 | DRA0175 | Proteobacterial affinity in DR; Cyanobacteria/Actinobacterial affinity in TT |
Threonine synthase (COG0498) | TTC0117 | DRA0360 | Proteobacterial version in DR; Cyanobacteria/Actinobacterial affinity in TT |
Trk system potassium uptake protein trkG, trkA (COG0168, COG0569) | TT0809, TT0810 | DR1667, DR1668; DR1666 | Archaeal version in TT; Gram-positive version in DR |
Ribonucleoside-diphosphate reductase alpha chain and beta chains (COG0208, COG0209) | TTP0162, TTP0161 | DRB0108, DRB0109 | Proteobacterial affinity for TT; affinity with Gram-positive bacteria in DR |
Paralogous genes acquisition | |||
5-formyltetrahydrofolate cyclo-ligase (COG0212) | TTC1247, TTC1803 | DR1815 | Gram-positive version in DR and TT; additional pseudoparalog TT1803 appears to be of archaeal origin |
Non-orthologous gene displacement/acquisition | |||
Thymidylate synthase | TTC0731 (COG1351) | DR2630 (COG0207) | Represented by two non-homologous genes in DR (protobacterial version) and TT (orthologs in Treponema, Wolbachia) |
Purine-nucleoside phosphorylase (purine degradation enzyme) | TTC1070 (COG0813) TTC0194 (COG0005) | DR2166 (COG0813) | TT has two non-homologous enzymes; TTC0194 probably was acquired from a thermopilic source |