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Figure 5 | BMC Evolutionary Biology

Figure 5

From: The complexity of selection at the major primate β-defensin locus

Figure 5

Structural implications of primate and mouse sites under significant selection. Each site is implicated by two or more programs from the following three: PAML, ADAPTSITE and SWAPSC. Primate sites were mapped to the structure of the human DEFB1 mature peptide (A) and mouse sites to the structure of the mouse Defb7 mature peptide (B). Sites subject to selection are depicted as inflated regions of the structures coloured red to indicate positive selection. The particular residues in DEFB1 and Defb7 corresponding to positively selected sites are also indicated with arrows. Ala (marked with an asterisk) is subject to negative and positive selection in different primate lineages.

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