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Figure 7 | BMC Evolutionary Biology

Figure 7

From: The integrins of the urochordate Ciona intestinalis provide novel insights into the molecular evolution of the vertebrate integrin family

Figure 7

Alignment of the refined Ciona β chain sequences with representative human orthologues (residues 543 to the C-terminus based on the human β1 integrin chain). Protein domains and conserved motifs are annotated. Levels of sequence conservation are indicated (>50% identical, red; conservative substitutions, blue). EGF domains 2–4, transmembrane (TM) domain, interaction and phosphotyrosine binding (PTB) motifs are indicated.

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