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Table 2 Correlations obtained from a direct comparison of S. cerevisiae with C. elegans Orthologues in the S. cerevisiae and C. elegans PINs where identified by reciprocal BLAST searches and evolutionary rates, estimated previously (see table 1), were analysed for correlation between evolutionary rate, the number of interactions and expression levels. We also performed an analysis with evolutionary rates estimated directly from the distant S. cerevisiae and C. elegans comparison.

From: Comparative analysis of the Saccharomyces cerevisiae and Caenorhabditis elegans protein interaction networks

Comparison

Evolutionary Rate obtained from closely related species

Evolutionary Rate obtained from S. cerevisiae- C. elegans

 

S. cerevisiae

C. elegans

S. cerevisiae

C. elegans

Nr. of Interactions

-0.11

-0.13

-0.20

-0.10

2.5-percentile

-0.20

-0.23

-0.26

-0.19

97.5-percentile

-0.02

-0.04

-0.14

-0.03

Expression

-0.33

-0.44

-0.25

-0.42

2.5-percentile

-0.41

-0.50

-0.32

-0.47

97.5-percentile

-0.24

-0.36

-0.19

-0.37