Table 7 Non-synonymous Changes on the 1A3/1A4 Branch
Site* | Nucleotide Changes/Site | Hominoid SULT1A Ancestor | Â | Hominoid SULT1A3 Ancestor | ||||
|---|---|---|---|---|---|---|---|---|
|  |  | Residue | PP†| Physicochemical Properties |  | Residue | PP | Physicochemical Properties |
44 | 1 | Ser | (1.00) | tiny polar | → | Asn | (1.00) | small polar |
71 | 1 | His | (0.99) | non-polar aromatic positive | → | Asn | (1.00) | small polar |
76 | 1 | Phe | (1.00) | non-polar aromatic | → | Tyr | (1.00) | aromatic |
77 | 2 | Met | (0.99) | non-polar | → | Val | (1.00) | small non-polar aliphatic |
84 | 1 | Phe | (1.00) | non-polar aromatic | → | Val | (1.00) | small non-polar aliphatic |
85 | 1 | Lys | (1.00) | Positive | → | Asn | (1.00) | small polar |
86 | 2 | Val | (0.98) | small non-polar aliphatic | → | Asp | (1.00) | small polar negative |
89 | 3 | Ile | (0.98) | non-polar aliphatic | → | Glu | (1.00) | polar negative |
93 | 1 | Met | (0.00) | non-polar | → | Leu | (1.00) | non-polar aliphatic |
101 | 1 | Ala | (1.00) | tiny non-polar | → | Pro | (1.00) | small |
105 | 1 | Leu | (1.00) | non-polar aliphatic | → | Ile | (1.00) | son-polar aliphatic |
107 | 1 | Thr | (1.00) | tiny polar | → | Ser | (1.00) | tiny polar |
132 | 1 | Ala | (1.00) | tiny non-polar | → | Pro | (1.00) | small |
143 | 1 | Tyr | (1.00) | aromatic | → | His | (1.00) | non-polar aromatic positive |
144 | 2 | His | (0.99) | non-polar aromatic positive | → | Arg | (1.00) | polar positive |
146 | 2 | Ala | (1.00) | tiny non-polar | → | Glu | (1.00) | polar negative |
148 | 1 | Val | (1.00) | small non-polar aliphatic | → | Ala | (1.00) | tiny non-polar |
222 | 1 | Leu | (0.99) | non-polar aliphatic | → | Phe | (1.00) | non-polar aromatic |