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Table 2 GenBank accession numbers for relaxin-like sequences. Accession numbers for all sequences included in the phylogeny are listed. New sequences identified in this study are highlighted in bold and accession numbers shown in brackets underneath. Phylogenetic analyses showed TrRLX3f, DrRLX3c, XtRLX3a and XlRLX3 sequences (shown in italics) to be relaxin rather than relaxin-3 homologs and are therefore listed in the relaxin (RLX2) column.

From: Evolution of the relaxin-like peptide family

Species

RLX1

RLX2

RLX3

INSL3

INSL4

INSL5

INSL6

Human

P04808

P04090

Q8WXF3

P51460

Q14641

Q9Y5Q6

Q9Y581

Chimpanzee

S42783

P51455

BK005156 b

BK005155 b

BK005152 b

BK005153 b

BK005154 b

Mouse

-

CAA81611

Q8CHK2

O09107

-

Q9WUG6

Q9QY05

Rat

-

J00780

Q8BFS3

AAD33663

-

-

Q9WV41

Dog

-

Q9TRM8

AAEX01023146

AAEX01022997

  

AAEX01053723

Wallaby

 

AAM22209

     

R. esculenta

 

CAC16108

     

Fugufish

 

RLX3f

BK005388 b

RLX3a-c

  

RLX3d,e

 

Zebrafish

 

RLX3c

BK005255 b

RLX3a

BK005228

  

RLX3b

BK005252a,b

RLX3d (b,c)

 

Chicken

  

RLX3a

BK005146a

  

RLX3b

BK005533b

 

Pig

 

P01348

Q8HY17

P51461

   

X. tropicalis

 

RLX3a

BK005229 a

RLX3b(b,d)

RLX3c(b,d)

    

X. laevis

 

RLX3

BK005230 a

     

O. mykiss

     

RLX3

BK005147a

 

M. mulatta

    

INSL4

BK005251a

  
  1. aSequences determined from multiple overlapping ESTs.
  2. bSequences determined from genomic data.
  3. cSequence from the Ensembl zebrafish genome assembly [68](GENSCAN00000013529 on supercontig NA8544).
  4. dSequence from the Xenopus genome v2.0 [58].