From: Reconstruction of ancestral protein sequences and its applications
Protein Family | PDB ID# | Ligand/ substrate | Number of sites | * | ** | *** | ANCESCON | ET | SC | CD |
---|---|---|---|---|---|---|---|---|---|---|
adkinase | 1aky | AP5 | 188 | 42 | 20 | 18 | 3 | 9.5 | 9.1 | 8 |
gef | 1bkd | H-Ras | 245 | 47 | 4 | 0 | 3 | 3 | 3 | 2 |
globin | 1a6g | HEM | 147 | 21 | 1 | 1 | 2 | 5.5 | 6 | 6 |
pdz | 1be9 | + | 81 | 15 | 2 | 1 | 6 | 4 | 4 | 2 |
ph | 1mai | I3P | 109 | 11 | 2 | 0 | 2 | 2 | 3 | 2 |
ptb | 1shc | PTR | 157 | 27 | 2 | 1 | 6 | 5 | 5 | 9 |
ras | 821p | GTN | 185 | 29 | 10 | 9 | 2 | 5.6 | 8.7 | 5 |
sh2 | 1a09 | ACE | 83 | 17 | 2 | 1 | 3 | 5 | 4 | 4 |
sh3 | 1nlo | ACE | 57 | 9 | 1 | 1 | 2 | 5 | 4 | 0 |
subtilase | 1av7 | SBL | 278 | 22 | 8 | 4 | 5 | 4.6 | 3.8 | 4 |