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Table 1 Difference of logarithm likelihood and CPU time when using different α vectors

From: Reconstruction of ancestral protein sequences and its applications

 

α = 1.0

α AB

α ML

   

Δl

P*

 

Δl

P*

Logarithm Likelihood

-5324.56

-5087.72

236.84

<0.0001

-4987.27

337.29

<0.0001

CPU Time (s)+

213

 

213

359

  1. The alignment tested here is a subset of SH2 family. It includes 44 sequences and each sequence contains 83 amino acids (including gaps).
  2. * The likelihood ratio test (LRT) [58] is used to test whether α AB and α ML are significantly different from α = 1.0. The difference in number of free parameters between α AB , α ML and α = 1.0 model is 82.
  3. + CPU times were computed on a Dell PowerEdge 8450 server (CPU 700MHz, RAM 8G).
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BMC Ecology and Evolution

ISSN: 2730-7182

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