From: Duplicated genes evolve slower than singletons despite the initial rate increase
Human – Mouse | Dup Obs-Exp | Dup (Obs-Exp)2/Exp | Sing Obs-Exp | Sing (Obs-Exp)2/Exp |
---|---|---|---|---|
Information storage and processing | -49.5 | 1.46 | 49.5 | 9.76 |
Cellular processes and signaling | 241.1 | 14.39 | -241.1 | 96.04 |
Metabolism | -11.9 | 0.09 | 11.9 | 0.58 |
Poorly characterized | -179.6 | 13.04 | 179.6 | 87.07 |
χ2 P | 222.43 6.0 × 10-48 | |||
Drosophila – Anopheles | Dup Obs-Exp | Dup (Obs-Exp)2/Exp | Sing Obs-Exp | Sing (Obs-Exp)2/Exp |
Information storage and processing | -93 | 9.75 | 93 | 26.48 |
Cellular processes and signaling | 124.8 | 9.29 | -124.8 | 25.25 |
Metabolism | 89.1 | 8.78 | -89.1 | 23.86 |
Poorly characterized | -120.9 | 12.69 | 120.9 | 34.46 |
χ2 P | 150.56 2.0 × 10-32 | |||
S. cerevisiae – C. albicans | Dup Obs-Exp | Dup (Obs-Exp)2/Exp | Sing Obs-Exp | Sing (Obs-Exp)2/Exp |
Information storage and processing | -38.6 | 3.50 | 38.6 | 3.63 |
Cellular processes and signaling | 55.4 | 5.68 | -55.4 | 5.89 |
Metabolism | 36.1 | 3.39 | -36.1 | 3.52 |
Poorly characterized | -52.9 | 9.19 | 52.9 | 9.53 |
χ2 P | 44.33 1.3 × 10-9 |