Table 4 Correlation between ortholog substitution levels and the substitution levels between the most closely related paralogs for lineage specific expansions (Figure 3)
From: Duplicated genes evolve slower than singletons despite the initial rate increase
Lineagea | Slopeb | r2c | P d |
|---|---|---|---|
Human specific (1-2a) | 2.0 × 10-1 | 7.8 × 10-2 | 1.6 × 10-34 |
Mammalian specific (2-2a) | 2.1 × 10-1 | 2.2 × 10-1 | 2.7 × 10-114 |
Vertebrate and before (3-2a) | 8.2 × 10-2 | 7.3 × 10-2 | 9.9 × 10-132 |
S. cerevisiae specific (1-2b) | 8.3 × 10-1 | 4.6 × 10-1 | 1.7 × 10-58 |
S. cerevisiae – C. albicans (2-2b) | 4.6 × 10-1 | 4.2 × 10-1 | 3.4 × 10-18 |
Yeast and before (3-2b) | 3.3 × 10-1 | 2.1 × 10-1 | 2.8 × 10-54 |