Figure 3
From: Compensatory mutations cause excess of antagonistic epistasis in RNA secondary structure folding
Function w(d) (left panel) and average neutrality (right panel) at distance d, for two reference sequences. Points are measurements, and lines represent best fits [function exp(- α dβ) for w(d), and function md + n for average neutrality]. (a): A case of strongly antagonistic epistasis (β = 0.688), which is associated with increasing neutrality with d (right panel). (b): A more synergistic case (β = 1.017), and a corresponding decline in neutrality with d.