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Figure 1 | BMC Evolutionary Biology

Figure 1

From: The tyranny of adenosine recognition among RNA aptamers to coenzyme A

Figure 1

Affinity matrices used in isolation of aptamers to adenosine cofactors. A) CoA attached to sepharose solid support through its pantotheine arm (disufide-linked CoA resin); B) CoA attached to sepharose through its primary amine at N6 (Amide-linked CoA resin); C) Other adenosine cofactors attached through the C8 of adenine. ATP, R = PPi; AMP, R = H, NAD+, R = nicotinamide mononucleotide.

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