Potential | Model |
y
|
x
|
AIC
| <w( AIC)> |
N
prot
|
<R>
|
<pR>
|
|---|
pfANM | Stress |
ω
|
MLmS
| 190508 | 0.97 | 206 | -0.54 | -0.33 |
| | Flexibility |
ω
|
MSF
| 198662 | 0.03 | 7 | 0.45 | -0.06 |
ANM | Stress |
ω
|
MLmS
| 194154 | 0.98 | 209 | -0.52 | -0.39 |
| | Flexibility |
ω
|
MSF
| 207258 | 0.02 | 4 | 0.35 | -0.04 |
- NOTE: Potential is the ENM potential, Model is either the Stress Model or Flexibility Model, y is in all cases the site-specific rate of evolution inferred using Rate4Site, x is the independent variable of each model. AIC is the Akaike Information Criterion summed over all proteins. <w(AIC)> is the average of the AIC weight for each compared model (same ENM). N
prot
is the number of proteins for which each compared model (same ENM) is the best one. <R> is average over proteins of Pearson’s correlation coefficient between variables y and x. <pR> is the average partial correlation coefficient when controlling for the x variable of the contrasting model (same ENM). All variables were z-score normalized for each protein before fitting.
