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Table 1 Codon usage bias indices for IPCS, SPL and SPT genes

From: Molecular evolution of the enzymes involved in the sphingolipid metabolism of Leishmania: selection pressure in relation to functional divergence and conservation

Enzyme name

Species

CAI

ENc

GC3S

FOP

Highest RSCU

IPCS

L.major

0.604

50.34

0.72

0.362

UUG (Leu)

L.donovani

0.623

48.61

0.70

0.385

CGC (Arg)

L.braziliensis

0.573

48.21

0.69

0.394

CGC (Arg)

SPL

L.major

0.681

44.22

0.78

0.39

CUG (Leu)

L.infactum

0.685

43.26

0.80

0.37

CGC (Arg)

SPT-1

L.major

0.694

46.45

0.77

0.323

CUG (Leu)

SPT-2

L.major

0.720

40.29

0.83

0.373

GUU (Val)

  1. RSCU (Relative synonymous codon usage was calculated to estimate the number of cotton under codon usage bias. CUB indices calculate are a) CAI – Codon adaptability index b) ENc – Effective number of codons c) GC3S – GC content at third synonymous position d) FOP – Frequency of optimized codons. A comparison of these indices between Leishmania and other homologous species is made. Range of indices between homologous species is given in the brackets. IPCS, SPT and SPL genes of Leishmania experience higher codon usage bias as compared to their homologues.