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Figure 2 | BMC Evolutionary Biology

Figure 2

From: Origin, evolution and classification of type-3 copper proteins: lineage-specific gene expansions and losses across the Metazoa

Figure 2

Phylogenetic analysis of the type-3 copper subclass proteins. A. A representative phylogenetic tree based on Bayesian Inference (BI), which is midpoint rooted. Statistical support is indicated at the nodes; first number, BI posterior probabilities; second number, ML bootstrap support; third number, NJ bootstrap support. Only statistical support values >50% are shown. Accession numbers of the proteins used in this tree can be found in Additional file 1. See Additional files 2, 3, 4 for detailed phylogenetic analyses of each type-3 copper protein subclass. B. Phylogenetic relationship and functionalities found in type-3 copper subclasses. T, tyrosinase; C, catechol oxidases; H, hemocyanin. Species were labelled according to a specific colour code as follows: black: Eubacteria; sky blue: Archaeobacteria; purple: Plantae; orange: Chromoalveaolata; dark blue: Amoebozoa; dark green: Fungi; yellow: Porifiera; light green: Cnidaria; magenta: Protostomia (Mollusca, Annelida, Platyhelminthes, Nematoda, Arthropoda and Onycophora); brown: Deuterostomia (Hemichordata, Cephalochordata, Urochordata and Vertebrata).

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